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How much weight can you lose with Wegovy?
Wegovy helps patients achieve significant weight loss when used long-term with lifestyle changes. Clinical trials show progressive results:
With consistent treatment, most users lose 10% of their starting weight in months 3-6 and 20% after 6 months. Individual outcomes vary based on adherence.
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Weeks 1–12 – Getting Started
- Begin lower dose with gradual increases
- 1-2 lbs/week as the body adjusts
- Building tolerance & healthy routines
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Months 3–6 – Visible Results
- Steady therapeutic dosing
- 5-10% of starting weight
- Visible changes & health improvements
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After 6 Months – Long-Term Success
- Full maintenance dose
- 15-20% of starting weight
- Sustaining results on your weight loss journey
Your Wegovy Treatment Plan: Safe & Effective Dosing
Our clinically proven Wegovy treatment plan follows the dosing schedule validated in New England Journal of Medicine studies. Gradual dose increases help minimise serious side effects like stomach pain or low blood sugar while supporting sustainable weight reduction.
Weekly Injection Schedule
All doses administered via Wegovy pen (in the upper arm, thigh or abdomen):
- Weeks 1–4: 0.25 mg (starting dose)
- Weeks 5–8: 0.5 mg
- Weeks 9–12: 1.0 mg
- Weeks 13–16: 1.7 mg
- Week 17 onwards: 2.4 mg (maintenance dose)
Personalised Dose Adjustments
"Different doses of Wegovy work best for different patients."
Suppose you're comfortably achieving your weight loss goal at a lower dose or experiencing side effects. In that case, our clinicians may adjust your plan. Many patients maintain results on doses below 2.4mg long-term.
Administering Your Wegovy: Simple Weekly Injection Guide
Wegovy delivers its active ingredient, semaglutide, through a convenient weekly injection. Proper technique ensures effective treatment while minimising discomfort. Always consult your patient information leaflet for full instructions before starting your Wegovy treatment.
Approved Injection Sites
Rotate between these areas weekly:
- Upper arm (back area, 2-3 inches below shoulder)
- Stomach (abdomen, 2 inches from navel)
- Upper thigh (front/midsection)

Essential Safety:
- Rotate sites weekly to prevent skin irritation
- Dispose of used needles in your sharps bin
- Never reuse needles or pens
Storing Your Wegovy Pens: Simple Safety Guide
At Chelsea Slimming Clinic, we ensure your weight loss injections arrive perfectly preserved through temperature-controlled delivery. Proper storage maintains the effectiveness of your Wegovy pens - follow these essential steps:
Refrigerated Storage (Before use)
- Keep pens at 2°C-8°C in the refrigerator
- Never freeze - place away from the freezer compartment
- Frozen pens become unusable
Room Temperature Storage (After First Use)
- Can store below 30°C for 42 days
- Ideal for travel or fridge-free periods
- Always keep the pen cap securely on
Critical Protection Measures
- Avoid direct sunlight or heat sources
- Never expose to temperatures >30°C
- Check the expiry date before each injection
Safe Disposal Protocol
- Dispose of all used Wegovy pens in your sharps bin
- Request sharps bin with the first delivery
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When ¾ full, return to:
- Local pharmacy
- GP surgery
- NHS collection point
Key Reminder : Always store out of children's reach, and never use expired pens.
Wegovy Safety Guide: Understanding Side Effects
At Chelsea Slimming Clinic, your well-being is paramount. While Wegovy weight loss injections deliver significant weight reduction, being informed about possible side effects ensures safe treatment. This guide covers what to expect during Wegovy use.
Common Side Effects of Wegovy
Most common side effects (usually mild/moderate):
- Nausea or vomiting (especially early weeks)
- Constipation/diarrhoea
- Headache or fatigue
- Stomach pain or bloating
- Indigestion/heartburn
- Injection site reactions
These typically improve within weeks as your body adjusts. Our step-up dosing minimises discomfort.
Serious Side Effects: When to Seek Help
Although rare, Wegovy may cause more serious side effects, which require immediate medical attention:
Symptom | Possible Condition |
---|---|
Vision changes | Diabetic retinopathy (in diabetic patients) |
Severe pains in abdomen/back | Pancreatitis |
Difficulty breathing/swelling | Severe allergic reaction |
Dark urine + abdominal pain | Kidney problems |
Sudden bone pain | Potential fractures |
Unrelenting vomiting + bloating | Bowel obstruction |
If you experience these symptoms, stop using Wegovy, seek urgent medical advice, or call 999.
Ongoing Safety Monitoring
Wegovy is currently under enhanced safety monitoring in the UK (indicated by the black triangle symbol). All common or uncommon side effects can be reported through the Yellow Card Scheme, helping improve safety for all users. Before starting treatment, your medical history will be reviewed in full, and you should also let us know if you’re taking any other prescription medications, including the contraceptive pill or any other weight loss medicines.